X0508 4 2025-12-23 0 0001448431 OptimizeRx Corp OPRX 0001773461 Silvestro Stephen L C/O OPTIMIZERX CORPORATION 260 CHARLES STREET, SUITE 302 WALTHAM MA 02453 0 1 0 0 Chief Executive Officer 0 Common Stock 2025-12-23 4 F 0 3361 12.74 D 190507 D These shares sold pursuant to a plan of disposition adopted on March 11, 2021 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended. These shares were withheld by the Issuer upon the vesting of restricted stock units to satisfy the Reporting Person's tax withholding obligations. Such withholding is treated as a disposition of securities under Section 16 of the Securities Exchange Act of 1934, as amended. The filing of this Statement shall not be construed as an admission (a) that the person filing this Statement is, for the purposes of Section 16 of the Securities Exchange Act of 1934, as amended, the beneficial owner of any equity securities covered by this Statement, or (b) that this Statement is legally required to be filed by such person. /s/ Marion Odence-Ford, by Power of Attorney 2025-12-23