X0609 4 2026-06-01 0001759425 Mirum Pharmaceuticals, Inc. MIRM 0001614740 Peetz Christopher false C/O MIRUM PHARMACEUTICALS, INC. 989 E HILLSDALE BLVD., SUITE 300 FOSTER CITY CA 94404 true true false false CHIEF EXECUTIVE OFFICER 1 Common Stock 2026-06-01 4 M 0 30000 2.936 A 224309 D Common Stock 2026-06-01 4 S 0 2602 94.64 D 221707 D Common Stock 2026-06-01 4 S 0 16595 95.34 D 205112 D Common Stock 2026-06-01 4 S 0 6926 96.15 D 198186 D Common Stock 2026-06-01 4 S 0 1973 97.56 D 196213 D Common Stock 2026-06-01 4 S 0 1021 98.20 D 195192 D Common Stock 2026-06-01 4 S 0 883 99.66 D 194309 D Common Stock 187500 I By The Peetz Family Trust Employee Stock Option (right to buy) 2.936 2026-06-01 4 M 0 30000 0 D 2029-03-11 Common Stock 30000 128487 D Reported transaction occurred pursuant to a Rule 10b5-1 Plan adopted by the reporting person on March 2, 2026. The weighted average sale price for the transaction reported was $94.64, and the range of prices were between $93.90 and $94.895. Upon request by the SEC staff, the Issuer, or any security holder of the Issuer, full information regarding the number of shares sold at each separate price will be provided. The weighted average sale price for the transaction reported was $95.34, and the range of prices were between $94.91 and $95.91. Upon request by the SEC staff, the Issuer, or any security holder of the Issuer, full information regarding the number of shares sold at each separate price will be provided. The weighted average sale price for the transaction reported was $96.15, and the range of prices were between $95.92 and $96.8675. Upon request by the SEC staff, the Issuer, or any security holder of the Issuer, full information regarding the number of shares sold at each separate price will be provided. The weighted average sale price for the transaction reported was $97.56, and the range of prices were between $96.98 and $97.94. Upon request by the SEC staff, the Issuer, or any security holder of the Issuer, full information regarding the number of shares sold at each separate price will be provided. The weighted average sale price for the transaction reported was $98.20, and the range of prices were between $98.00 and $98.38. Upon request by the SEC staff, the Issuer, or any security holder of the Issuer, full information regarding the number of shares sold at each separate price will be provided. The weighted average sale price for the transaction reported was $99.66, and the range of prices were between $99.55 and $99.79. Upon request by the SEC staff, the Issuer, or any security holder of the Issuer, full information regarding the number of shares sold at each separate price will be provided. The stock option is fully vested. /s/ Judit Ryvkin, Attorney-in-Fact 2026-06-02