X0508 4 2026-03-01 0001628171 Revolution Medicines, Inc. RVMD 0001462808 Kelsey Stephen Michael C/O REVOLUTION MEDICINES, INC. 700 SAGINAW DRIVE REDWOOD CITY CA 94063 true See Remarks false Common Stock 2026-03-01 4 A 0 21100 0 A 299700 D Stock Option (Right to Buy) 102.02 2026-03-01 4 A 0 47600 0 A 2036-02-28 Common Stock 47600 47600 D Includes 94,676 restricted stock units. One forty-eighth (1/48th) of the shares initially subject to the option will vest on each monthly anniversary measured from March 1, 2026 (the "Vesting Commencement Date"), so that 100% of the shares subject to the option will be fully vested and exercisable as of the fourth anniversary of the Vesting Commencement Date, subject to the Reporting Person's continued service through each vesting date. President, Research and Development /s/ Jack Anders, as Attorney-in-fact for Stephen Michael Kelsey 2026-03-03