X0508 4 2025-12-19 0 0001326732 Xencor Inc XNCR 0001591312 Dahiyat Bassil I C/O XENCOR, INC. 465 N HALSTEAD STREET, SUITE 200 PASADENA CA 91107 1 1 0 0 PRESIDENT & CEO 0 Common Stock 2025-12-19 4 M 0 114377 12.51 A 581012 D Common Stock 2025-12-19 4 S 0 114377 15.71 D 466635 D Common Stock 2025-12-22 4 M 0 10624 12.51 A 477259 D Stock Option (Right to Buy) 12.51 2025-12-19 4 M 0 114377 0 D 2026-01-26 Common Stock 114377 10624 D Stock Option (Right to Buy) 12.51 2025-12-22 4 M 0 10624 0 D 2026-01-26 Common Stock 10624 0 D Includes the following shares acquired by the Reporting Person pursuant to the Issuer's Employee Stock Purchase Plan: 707 shares acquired on June 10, 2025 and 509 shares on December 10, 2025. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $15.52 to $15.92, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote. Represents the exercise of an expiring option grant. 25% of the shares subject to the option vested on the one year anniversary of January 26, 2016 (the "Vesting Commencement Date"), and 1/48th of the shares vested monthly thereafter, such that the option was fully vested and exercisable on the four year anniversary of the Vesting Commencement Date. The Reporting Person previously transferred 124,999 shares underlying the stock option to his ex-spouse. The Reporting Person no longer reports as beneficially owned any securities owned by his ex-spouse. /s/ Celia E. Eckert, Attorney-in-Fact 2025-12-23