X0508 4 2026-02-24 0 0001356576 SUPERNUS PHARMACEUTICALS, INC. SUPN 0001539215 Bhatt Padmanabh P. C/O SUPERNUS PHARMACEUTICALS, INC. 9715 KEY WEST AVENUE ROCKVILLE MD 20850 0 1 0 0 Sr. VP of IP, CSO 0 Common Stock 2026-02-24 4 A 0 1125 0 A 16025 D Common Stock 2026-02-24 4 F 0 581 51.35 D 15444 D Common Stock 2026-02-24 4 A 0 750 0 A 16194 D Common Stock 2026-02-24 4 F 0 354 50.86 D 15840 D Common Stock 2026-02-24 4 A 0 1250 0 A 17090 D Common Stock 2026-02-24 4 F 0 646 50.86 D 16444 D Restricted Stock Unit 2026-02-24 4 D 0 1125 0 D Common Stock 1125 3375 D Restricted Stock Unit 2026-02-24 4 D 0 750 0 D Common Stock 750 0 D Restricted Stock Unit 2026-02-24 4 D 0 1250 0 D Common Stock 1250 2500 D Represents the number of shares of common stock withheld by the Company to satisfy tax withholding requirements in connection with the RSU vesting. Each restricted stock unit represents the right to receive one share of Supernus common stock upon vesting. These restricted stock units are settled in common stock upon vesting, which occurs in four equal annual installments, beginning on February 19, 2026. These restricted stock units are settled in common stock upon vesting, which occurs in four equal annual installments, beginning on February 22, 2023. These restricted stock units are settled in common stock upon vesting, which occurs in four equal annual installments, beginning on February 22, 2025. /s/ Timothy C. Dec, as attorney-in-fact 2026-02-25