X0609 4 2026-04-28 0001730430 Kiniksa Pharmaceuticals International, plc KNSA 0001532218 Patel Sanj K true C/O KINIKSA PHARMACEUTICALS INT'L 105 PICCADILLY, SECOND FLOOR LONDON X0 W1J 7NJ UNITED KINGDOM true true false false CHAIRMAN & CEO 1 Class A Ordinary Share 2026-04-28 4 M 0 431904 10.36 A 431904 D Class A Ordinary Share 2026-04-28 4 M 0 51750 30.93 A 483654 D Class A Ordinary Share 2026-04-28 4 S 0 74635 50.43 D 409019 D Class A Ordinary Share 2026-04-28 4 S 0 113673 51.47 D 295346 D Class A Ordinary Share 2026-04-28 4 S 0 243596 52.02 D 51750 D Class A Ordinary Share 2026-04-28 4 S 0 51750 54.02 D 0 D Class A Ordinary Share 2026-04-29 4 M 0 22544 30.93 A 22544 D Class A Ordinary Share 2026-04-29 4 S 0 22544 54.01 D 0 D Class A Ordinary Share 2026-04-30 4 M 0 2141 30.93 A 2141 D Class A Ordinary Share 2026-04-30 4 S 0 2141 54.01 D 0 D Class A Ordinary Share 76174 I Held by The Patel Family Irrevocable Trust of 2025 Class A Ordinary Share 109795 I Held by The Marina 2016 Irrevocable Trust, u/d/t June 23, 2016 Class A Ordinary Share 51794 I Held by The Anglia 2013 Revocable Trust Share Option 10.36 2026-04-28 4 M 0 431904 0 D 2028-02-29 Class A Ordinary Share 431904 0 D Share Option 30.93 2026-04-28 4 M 0 51750 0 D 2028-09-19 Class A Ordinary Share 51750 73250 D Share Option 30.93 2026-04-29 4 M 0 22544 0 D 2028-09-19 Class A Ordinary Share 22544 50706 D Share Option 30.93 2026-04-30 4 M 0 2141 0 D 2028-09-19 Class A Ordinary Share 2141 48565 D This transaction was effected pursuant to a 10b5-1 plan executed by the reporting person on October 31, 2025. This transaction was executed in multiple trades through a broker-dealer at prices ranging between $50.00 and $50.985. The price reported in this column reflects a weighted average sales price. Upon request, the reporting person will provide to the SEC staff full information regarding the number of Shares sold at each price. This transaction was executed in multiple trades through a broker-dealer at prices ranging between $51.00 and $51.99. The price reported in this column reflects a weighted average sales price. Upon request, the reporting person will provide to the SEC staff full information regarding the number of Shares sold at each price. This transaction was executed in multiple trades through a broker-dealer at prices ranging between $52.00 and $52.58. The price reported in this column reflects a weighted average sales price. Upon request, the reporting person will provide to the SEC staff full information regarding the number of Shares sold at each price. This transaction was executed in multiple trades through a broker-dealer at prices ranging between $54.00 and $54.22. The price reported in this column reflects a weighted average sales price. Upon request, the reporting person will provide to the SEC staff full information regarding the number of Shares sold at each price. This transaction was executed in multiple trades through a broker-dealer at prices ranging between $54.00 and $54.225. The price reported in this column reflects a weighted average sales price. Upon request, the reporting person will provide to the SEC staff full information regarding the number of Shares sold at each price. This transaction was executed in multiple trades through a broker-dealer at prices ranging between $54.00 and $54.03. The price reported in this column reflects a weighted average sales price. Upon request, the reporting person will provide to the SEC staff full information regarding the number of Shares sold at each price. The option is fully vested and exercisable. /s/ Douglas Barry, Attorney-in-Fact 2026-04-30