X0508 4 2025-10-27 0001411685 Vistagen Therapeutics, Inc. VTGN 0001531178 Edick Paul R C/O VISTAGEN THERAPEUTICS, INC. 343 ALLERTON AVENUE SOUTH SAN FRANCISCO CA 94080 true false false false 0 Stock Option (Right to Buy) 3.90 2025-10-27 4 A 0 35200 A 2035-10-27 Common Stock 35200 35200 D Represents stock options granted in connection with the reporting person's appointment to the Issuer's Board of Directors. The stock options were granted pursuant to the Issuer's Amended and Restated 2019 Omnibus Equity Incentive Plan, as amended, and vest in three equal annual installments, beginning on the first anniversary of the date of the grant. /s/ Paul R. Edick 2025-11-04