X0609 4 2026-06-30 0 0001567264 INTENSITY THERAPEUTICS, INC. INTS 0001524547 Talamo Joseph false C/O INTENSITY THERAPEUTICS, INC. 1 ENTERPRISE DRIVE, SUITE 430 SHELTON CT 06484 0 1 0 0 Chief Financial Officer 0 Common Stock, $0.0001 Par Value 2026-06-30 5 A 0 E 1093 3.485 A 2239 D The Reporting Person is voluntarily reporting the acquisition of shares under the Issuer's Amended and Restated 2024 Employee Stock Purchase Plan (ESPP) in a transaction exempt under Rule 16b-3(c) and Rule 16b-3(d). In accordance with the ESPP, these shares were purchased at a price equal to 85% of the closing price of the Issuer's common stock on June 30, 2026. On February 18, 2026, the Issuer effectuated a 1-for-25 reverse split of the Issuer's common stock resulting in a reduction in the number of shares held by the Reporting Person. In addition, proportionate adjustments were made to the Issuer's outstanding equity awards. Accordingly, all amounts of securities reported in this Form 4 have been adjusted to reflect the 1-for-25 reverse split. /s/ Joseph Talamo 2026-07-01