X0508 4 2025-10-28 0 0001412486 Cocrystal Pharma, Inc. COCP 0001510224 Martin James Joseph 4400 BISCAYNE BLVD SUITE # 670 MIAMI FL 33157 0 1 0 0 Co-CEO and CFO 0 Common Stock 2025-10-28 4 A 0 3598 1.39 A 44167 D Warrants 1.24 2025-10-28 4 A 0 7196 1.39 A 2028-01-28 Common Stock 7196 7196 D The Reporting Person purchased units at $1.39 per unit with each unit consisting of one share of common stock and a warrant to purchase two shares of common stock. The shares of common stock and warrants purchased are exempt from Section 16(b) of the Securities Exchange Act of 1934 by virtue of Rule 16b-3 thereunder, as it was approved by a Special Committee of the Board of Directors of the Issuer, which Special Committee consisted of two non-employee directors. The warrants were exercisable upon issuance. Includes shares of common stock issuable upon vesting of restricted stock units. /s/ James Martin 2025-10-30