X0609 4 2026-06-22 0 0001490978 Schrodinger, Inc. SDGR 0001275887 OBEROI ARUN false C/O SCHRODINGER, INC., 1540 BROADWAY, 24TH FLOOR NEW YORK NY 10036 1 0 0 0 0 Common Stock 2026-06-22 4 A 0 8141 0 A 25388 D Stock Option (right to buy) 15.23 2026-06-22 4 A 0 13313 0 A 2036-06-22 Common Stock 13313 13313 D Grant of restricted stock units ("RSUs") under the Issuer's 2022 Equity Incentive Plan, as amended. Each RSU represents a contingent right to receive one share of common stock of the Issuer. The RSUs were granted on June 22, 2026 and shall vest on the twelve-month anniversary of the date of grant of the award (or, if earlier, the date of the next annual meeting of stockholders following the date of grant of the award), subject to continued service. Includes 8,141 unvested RSUs. The option was granted on June 22, 2026 under the Issuer's 2022 Equity Incentive Plan, as amended. The award shall vest on the twelve-month anniversary of the date of grant of the award (or, if earlier, the date of the next annual meeting of stockholders following the date of grant of the award), subject to continued service. /s/ Donald Shum, as attorney-in-fact for Arun Oberoi 2026-06-23