X0508 4 2025-12-31 1 0001434647 ZEVRA THERAPEUTICS, INC. ZVRA 0001488774 Clifton R. LaDuane C/O ZEVRA THERAPEUTICS, INC. 1180 CELEBRATION BOULEVARD, SUITE 103 CELEBRATION FL 34747 0 0 0 1 Former CFO & Treasurer 0 Common Stock 2025-12-31 4 M 0 140667 0 A 192028 D Common Stock 2025-12-31 4 F 0 48513 8.96 D 143515 D Restricted Stock Unit 2025-12-31 4 M 0 86667 0 D Common Stock 86667 0 D Restricted Stock Unit 2025-12-31 4 M 0 34000 0 D Common Stock 34000 0 D Performance Stock Unit 2025-12-31 4 M 0 20000 0 D Common Stock 20000 0 D Shares issued upon vesting of restricted stock units and performance stock units on December 31, 2025. Shares withheld to cover withholding taxes for the vested restricted stock units and performance stock units. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock. The vesting of all restricted stock units and performance stock units was accelerated upon the Reporting Person's departure from the Company on December 31, 2025. Each performance stock unit represents a contingent right to receive one share of the Issuer's common stock. /s/ R. LaDuane Clifton 2026-01-07