X0609 4 2026-08-05 0 0002131524 Braveheart Bio, Inc. BRVE 0001845681 Murdoch Travis false C/O BRAVEHEART BIO, INC. ONE LETTERMAN DR., BLDG. A, SUITE A4-300 SAN FRANCISCO CA 94129 1 1 0 0 CEO and President 0 Common Stock 2026-08-07 4 P 0 83333 18 A 2940670 D Common Stock 3338175 I By Murdoch Family Trust Common Stock 1027396 I By Irrevocable Gift Trust for Alizee Common Stock 1027396 I By Irrevocable Gift Trust for Siena Stock Option (Right to Buy) 19.80 2026-08-05 4 A 0 550000 0 A 2031-08-04 Common Stock 550000 550000 D The Reporting Person disclaims beneficial ownership of such securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), except to the extent of his pecuniary interest therein, if any. This report shall not be deemed an admission that the Reporting Person is the beneficial owner of such securities for purposes of Section 16 of the Exchange Act or for any other purpose. 1/48th of the shares subject to such option vest and become exercisable in substantially equal monthly installments on each monthly anniversary of July 23, 2026, subject to the Reporting Person's continuous service to the Issuer on each such date. /s/ James Paul Rickey, Attorney-in-Fact 2026-08-07