X0609 4 2026-04-14 0001815442 Kymera Therapeutics, Inc. KYMR 0001451612 Booth Bruce false C/O KYMERA THERAPEUTICS, INC. 500 NORTH BEACON STREET, FLOOR 4 WATERTOWN MA 02472 true false false false 1 Common Stock 2026-04-14 4 M 0 4159 14.18 A 4159 D Common Stock 2026-04-14 4 S 0 4159 89.97 D 0 D Common Stock 2026-04-15 4 M 0 2200 14.18 A 2200 D Common Stock 2026-04-15 4 S 0 2200 89.95 D 0 D Common Stock 2026-04-15 4 S 0 2750 90.10 D 3899917 I See footnote Common Stock 2026-04-15 4 S 0 385 90.10 D 674956 I See footnote Stock Option (Right to Buy) 14.18 2026-04-14 4 M 0 4159 0 D 2032-06-15 Common Stock 4159 7841 D Stock Option (Right to Buy) 14.18 2026-04-15 4 M 0 2200 0 D 2032-06-15 Common Stock 2200 5641 D This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 16, 2025. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $89.95 to $90.10 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold each separate price within the ranges set forth in footnotes (2), (3) and (5). The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $89.95 to $90.00 inclusive. This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 11, 2025. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $90.05 to $90.145 inclusive. These shares are held directly by Atlas Venture Fund X, L.P. ("Atlas Venture Fund X"). The general partner of Atlas Venture Fund X is Atlas Venture Associates X, L.P. ("AVA X LP"). Atlas Venture Associates X, LLC ("AVA X LLC") is the general partner of AVA X LP. The Reporting Person is a member of AVA X LLC and disclaims Section 16 beneficial ownership of the securities held by Atlas Venture Fund X, except to the extend of his pecuniary interest therein, if any. The shares are owned directly by Atlas Venture Opportunity Fund I, L.P. ("AVOF"). Atlas Venture Associates Opportunity I, L.P. ("AVAO LP") is the general partner of AVOF. Atlas Venture Associates Opportunity I, LLC ("AVAO LLC") is the general partner of AVAO LP. The Reporting Person is a member of AVAO LLC and disclaims Section 16 beneficial ownership of such securities held by AVOF, except to the extent of his pecuniary interest therein, if any. Fully vested and exercisable. /s/ Ommer Chohan, as Attorney-in-Fact 2026-04-16