X0609 4 2026-09-18 0 0001447028 Arbutus Biopharma Corp ABUS 0002063445 Nguyen Tuan false C/O ARBUTUS BIOPHARMA CORPORATION 701 VETERANS CIRCLE WARMINSTER PA 18974 0 1 0 0 Chief Financial Officer 0 Common Shares 2026-09-18 4 M 0 265625 3.49 A 339125 D Common Shares 2026-09-18 4 M 0 27475 4.39 A 366600 D Common Shares 2026-09-18 4 F 0 206637 5.07 D 159963 D Stock Option (Right to Buy) 3.49 2026-09-18 4 M 0 265625 0 D 2035-03-31 Common Shares 265625 484375 D Stock Option (Right to Buy) 4.39 2026-09-18 4 M 0 27475 0 D 2036-02-02 Common Shares 27475 160925 D The Reporting Person exercised options on September 18, 2026. The Issuer withheld an aggregate of 206,637 shares otherwise issuable upon the exercises to satisfy the aggregate exercise prices. The option, representing a right to purchase a total of 750,000 shares, vests over a four-year period, with 25% of the total shares subject to the option vesting on the 1st anniversary of the March 31, 2025 grant date and the remaining 75% vesting over the subsequent three-year period in substantially equal monthly installments at a rate of 1/48th of the total shares subject to the option each month, subject to the Reporting Person's continuous service as of each vesting date. The option, representing a right to purchase a total of 188,400 shares, vests over a four-year period, with 1/48th of the shares subject to the option vesting in substantially equal monthly installments measured from one month following the February 2, 2026 grant date, subject to the Reporting Person's continuous service as of each vesting date. /s/ Tuan Nguyen 2026-09-23