X0508 4/A 2026-02-02 2026-02-04 0001408443 Milestone Pharmaceuticals Inc. MIST 0001437782 Oliveto Joseph C/O MILESTONE PHARMACEUTICALS INC. 1111 DR. FREDERIK-PHILIPS BLVD, STE 420 MONTREAL A8 H4M 2X6 QUEBEC, CANADA true true false false President and CEO 0 Employee Stock Option (right to buy) 1.96 2026-02-02 4 A 0 679000 0 A 2036-02-02 Common Shares 679000 679000 D The exercise price on the initial filings was incorrectly stated. One-fourth (1/4th) of the shares subject to the option vest on February 2, 2027, and one thirty-sixth (1/36th) of the remaining shares subject to this option shall vest each month thereafter, subject to the Reporting Person continuing to provide service through each such date. /s/ Joseph Oliveto 2026-02-05