X0508 4 2025-01-28 0001645469 Monopar Therapeutics MNPR 0001727334 Robinson Chandler 1000 SKOKIE BLVD SUITE 350 WILMETTE IL 60091 1 1 Chief Executive Officer 0 Common Stock 85718 D Common Stock 2025-01-28 4 J 0 62815 0 A 62815 I See Footnote Pro rata liquidating distribution from Tactic Pharma, LLC ("Tactic"), of which the reporting person is a non-controlling member. In prior reports, the reporting person reported beneficial ownership of 272,026 shares of Monopar Therapeutics Inc. common stock held by Tactic. Represents shares held by the Chandler D. Robinson Irrevocable Trust U/A dated May 20, 2020. /s/ Quan Vu, Attorney-in-fact 2026-01-30