X0508 4 2025-12-11 0 0001174940 ORAGENICS INC OGEN 0001382225 Telling Fred 1990 MAIN STREET, SUITE 750 SARASOTA FL 34236 1 0 0 0 0 Common Stock 2025-12-12 4 S 0 210 0.9446 D 34538 D Non-Employee Director Option (Right to Buy) 0.93 2025-12-11 4 A 0 125000 0 A 2025-12-11 2035-12-11 Common Stock 125000 125000 D The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions ranging from $0.9440 to $0.9451. The reporting person undertakes to provide the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth above. Represents an award of options to purchase shares of the Company's Common Stock under the Company's 2021 Equity Incentive Plan, as amended, pursuant to the Company's non-employee director compensation program. The options vest immediately. The option exercise price is the Company's closing price on the date of grant. /s/ Julio C. Esquivel as Attorney-In-Fact for Fred Telling 2025-12-15