X0609 4 2026-07-30 0001645460 Cue Biopharma, Inc. CUE 0001320383 Ahlers James M false C/O CUE BIOPHARMA, INC. 40 GUEST STREET BOSTON MA 02135 false true false false Chief Financial Officer 0 Common Stock 2026-07-30 4 A 0 25500 0 A 25500 D Stock Option (Right to Buy) 30.40 2026-07-30 4 A 0 51000 0 A 2036-07-30 Common Stock 51000 51000 D Represents the grant of restricted stock units ("RSUs"). The shares subject to the RSU vest in equal quarterly installments over four years from July 30, 2026, subject to the reporting person's continued service with the issuer through each vest date. The stock option becomes exercisable in equal quarterly installments over four years from July 30, 2026, subject to the reporting person's continued service with the issuer through each vest date. /s/ Michael Meluzio, Attorney-in-Fact 2026-08-03