X0609 4 2026-06-08 0001534969 SERA PROGNOSTICS, INC. SERA 0001306386 Lawrence Sandra AJ false C/O SERA PROGNOSTICS, INC. 2749 EAST PARLEYS WAY, SUITE 200 SALT LAKE CITY UT 84109 true false false false true Class A Common Stock 2026-06-08 4 S false 1560 2.15 D 16473 D The transaction(s) reported on this Form 4 was/were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 10, 2025. The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $2.10 to $2.23, inclusive. The Reporting Person will provide to the staff of the Securities and Exchange Commission, the issuer, or any security holder of the issuer, upon request, full information regarding the number of shares sold at each separate price. /s/ Benjamin G. Jackson, Attorney-in-fact 2026-06-09