X0609 4 2026-05-27 0 0001816590 COMPASS Pathways plc CMPS 0001276038 SANTINI GINO true C/O COMPASS PATHWAYS PLC 33 BROADWICK ST. LONDON X0 W1FODQ UNITED KINGDOM 1 0 0 0 0 Share Option (Right to Buy) 11.85 2026-05-27 4 A 0 30158 0 A 2027-05-27 2036-05-26 Ordinary Shares 30158 30158 D The shares underlying this option vest in full upon the earlier to occur of (i) the first anniversary of the date of grant or (ii) the date of COMPASS Pathways plc's Annual General Meeting of Shareholders in 2027. The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents one Ordinary Share. /s/ Meredith Prithviraj by Power of Attorney for Gino Santini 2026-05-29