X0609 4 2026-06-23 0001620463 LeonaBio, Inc. LONA 0001258693 PICKERING GRANT false C/O LEONABIO, INC. 18706 NORTH CREEK PARKWAY, SUITE 104 BOTHELL WA 98011 true false false false 0 Stock Option (Right to Buy) 8.35 2026-06-23 4 A 0 28000 0 A 2036-06-22 Common Stock 28000 28000 D The shares subject to the option will vest on the earlier of (i) June 23, 2027, or (ii) the day immediately before the date of the next annual meeting of the Issuer's stockholders that occurs after June 22, 2026. The option reported was granted pursuant to the terms of the Issuer's Outside Director Compensation Policy. /s/ Mark Worthington, Attorney in fact for Grant Pickering 2026-06-24