X0609 4 2026-08-07 0001637715 OnKure Therapeutics, Inc. OKUR 0001240122 GREY MICHAEL G false C/O ONKURE THERAPEUTICS, INC. 6707 WINCHESTERR CIRCLE, SUITE 400 BOULDER CO 80301 true false false false 0 Stock Option (right to buy) 4.14 2026-08-07 4 A 0 22350 0 A 2036-08-06 Class A Common Stock 22350 22350 D 100% of the shares subject to the option will vest on the earlier of June 4, 2027 or the day prior to the date of the Issuer's next annual meeting of stockholders, subject to the Reporting Person continuing as a service provider through the applicable vesting date. /s/ Rogan Nunn, by power of attorney 2026-08-11