X0609 4 2026-08-10 0002056611 Latigo Biotherapeutics, Inc. LTGO 0001753037 5AM Ventures VI, L.P. false C/O 5AM VENTURE MANAGEMENT, LLC 4 EMBARCADERO CENTER, SUITE 3110 SAN FRANCISCO CA 94111 false false true false 0001829051 5AM Partners VI, LLC false C/O 5AM VENTURE MANAGEMENT, LLC 4 EMBARCADERO CENTER, SUITE 3110 SAN FRANCISCO CA 94111 0 0 1 0 0001844401 5AM Opportunities II, L.P. false C/O 5AM VENTURE MANAGEMENT, LLC 4 EMBARCADERO CENTER, SUITE 3110 SAN FRANCISCO CA 94111 0 0 1 0 0001873515 5AM Opportunities II (GP), LLC false C/O 5AM VENTURE MANAGEMENT, LLC 4 EMBARCADERO CENTER, SUITE 3110 SAN FRANCISCO CA 94111 0 0 1 0 0001664281 PARMAR KUSH false C/O 5AM VENTURE MANAGEMENT, LLC 4 EMBARCADERO CENTER, SUITE 3110 SAN FRANCISCO CA 94111 0 0 1 0 0001598549 Schwab Andrew J. false C/O 5AM VENTURE MANAGEMENT, LLC 4 EMBARCADERO CENTER, SUITE 3110 SAN FRANCISCO CA 94111 0 0 1 0 0 Common Stock 2026-08-10 4 C 0 4975543 A 4975543 I By 5AM Ventures VI, L.P. Common Stock 2026-08-10 4 C 0 2350419 A 2350419 I By 5AM Opportunities II, L.P. Series A Preferred Stock 2026-08-10 4 C 0 3152305 0 D Common Stock 3152305 0 I By 5AM Ventures VI, L.P. Series A-2 Preferred Stock 2026-08-10 4 C 0 1823238 0 D Common Stock 1823238 0 I By 5AM Ventures VI, L.P. Series A-2 Preferred Stock 2026-08-10 4 C 0 866018 0 D Common Stock 866018 0 I By 5AM Opportunities II, L.P. Series B Preferred Stock 2026-08-10 4 C 0 1484401 0 D Common Stock 1484401 0 I By 5AM Opportunities II, L.P. Each share of Series A Preferred Stock, Series A-2 Preferred Stock and Series B Preferred Stock automatically converted into Common Stock immediately prior to the closing of the Issuer's initial public offering for no additional consideration, on a one-for-one basis. The Series A Preferred Stock, Series A-2 Preferred Stock and Series B Preferred Stock had no expiration date. The securities are directly held by 5AM Ventures VI, L.P. ("Ventures VI"). 5AM Partners VI, LLC ("Partners VI") is the sole general partner of Ventures VI. Dr. Kush Parmar and Andrew J. Schwab are the managing members of Partners VI and may be deemed to have shared voting and investment power over the securities beneficially owned by Ventures VI. Each of Partners VI, Dr. Parmar, and Mr. Schwab disclaims beneficial ownership of such securities except to the extent of its or his respective pecuniary interest therein. The securities are directly held by 5AM Opportunities II, L.P. ("Opportunities II"). 5AM Opportunities II (GP), LLC ("Opportunities II GP") is the general partner of Opportunities II and may be deemed to have sole investment and voting power over the securities held by Opportunities II. Dr. Kush Parmar and Andrew J. Schwab are the managing members of Opportunities II GP and may be deemed to have shared voting and investment power over the securities beneficially owned by Opportunities II. Each of Opportunities II GP, Dr. Parmar, and Mr. Schwab disclaims beneficial ownership of such securities except to the extent of its or his respective pecuniary interest therein. 5AM Ventures VI, L.P., By 5AM Partners VI, LLC, its General Partner, By /s/ Kush Parmar, Managing Member 2026-08-12 5AM Partners VI, LLC, By /s/ Kush Parmar, Managing Member 2026-08-12 5AM Opportunities II, L.P., By 5AM Opportunities II (GP), LLC, its General Partner, By /s/ Kush Parmar, Managing Member 2026-08-12 5AM Opportunities II (GP), LLC, By /s/ Kush Parmar, Managing Member 2026-08-12 /s/ Kush Parmar 2026-08-12 /s/ Andrew J. Schwab 2026-08-12