X0609 4 2026-06-12 0001785530 Werewolf Therapeutics, Inc. HOWL 0001346824 RA CAPITAL MANAGEMENT, L.P. false 200 BERKELEY STREET, 18TH FLOOR BOSTON MA 02116 false false true false 0001315082 RA Capital Healthcare Fund LP false 200 BERKELEY STREET, 18TH FLOOR BOSTON MA 02116 0 0 1 0 0001384859 Kolchinsky Peter false C/O RA CAPITAL MANAGEMENT, L.P. 200 BERKELEY STREET, 18TH FLOOR BOSTON MA 02116 0 0 1 0 0001619841 Shah Rajeev M. false C/O RA CAPITAL MANAGEMENT, L.P. 200 BERKELEY STREET, 18TH FLOOR BOSTON MA 02116 0 0 1 0 0 Common Stock 2026-06-12 4 S 0 159119 0.40 D 4917566 I See footnotes Common Stock 2026-06-12 4 S 0 11322 0.40 D 349907 I See footnotes Common Stock 2026-06-15 4 S 0 120216 0.39 D 4797350 I See footnotes Common Stock 2026-06-15 4 S 0 8554 0.39 D 341353 I See footnotes Common Stock 2026-06-16 4 S 0 139686 0.37 D 4657664 I See footnotes Common Stock 2026-06-16 4 S 0 9939 0.37 D 331414 I See footnotes The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $0.3814 to $0.4129 inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. Held directly by RA Capital Healthcare Fund, L.P. (the "Fund"). RA Capital Management, L.P. (the "Adviser") is the investment manager for the Fund and RA Capital Nexus Fund II, L.P. (the "Nexus Fund II"). The general partner of the Adviser is RA Capital Management GP, LLC (the "Adviser GP"), of which Dr. Peter Kolchinsky and Mr. Rajeev Shah are the managing members. The Adviser, the Adviser GP, the Fund, Dr. Kolchinsky and Mr. Shah disclaim beneficial ownership of the reported securities, except to the extent of their respective pecuniary interest therein. Held directly by Nexus Fund II. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $0.3757 to $0.3955 inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $0.3584 to $0.3906 inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. /s/ Peter Kolchinsky, Manager of RA Capital Management, L.P. 2026-06-16 /s/ Peter Kolchinsky, Manager of RA Capital Healthcare Fund GP, LLC, the General Partner of RA Capital Healthcare Fund, L.P. 2026-06-16 /s/ Peter Kolchinsky, individually 2026-06-16 /s/ Rajeev Shah, individually 2026-06-16