X0508 4 2026-02-12 0001581280 Twist Bioscience Corp TWST 0001755970 Finn Patrick John C/O TWIST BIOSCIENCE CORPORATION 681 GATEWAY BLVD. SOUTH SAN FRANCISCO CA 94080 false true false false President and COO 1 Common Stock 2026-02-12 4 M false 1000 23.33 A 308788 D Common Stock 2026-02-12 4 M false 1500 26.66 A 310288 D Common Stock 2026-02-12 4 S false 3500 50.225 D 306788 D Common Stock 2026-02-13 4 M false 500 23.33 A 307288 D Common Stock 2026-02-13 4 M false 712 26.66 A 308000 D Common Stock 2026-02-13 4 S false 1750 50.041 D 306250 D Stock Option (right to buy) 26.66 2026-02-12 4 M false 1500 0 D 2028-11-18 Common Stock 1500 33012 D Stock Option (right to buy) 23.33 2026-02-12 4 M false 1000 0 D 2029-10-23 Common Stock 1000 18705 D Stock Option (right to buy) 26.66 2026-02-13 4 M false 712 0 D 2028-11-18 Common Stock 712 32300 D Stock Option (right to buy) 23.33 2026-02-13 4 M false 500 0 D 2029-10-23 Common Stock 500 18052 D The transactions reported on this Form 4 were affected pursuant to a Rule 10b5-1 trading plan previously adopted by the Reporting Person on May 13, 2025. Represents the weighted average sales price per share. The shares sold at prices ranging from $50.00 to $50.51 per share. Full information regarding the number of shares sold at each price shall be provided upon request to the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer. The option is immediately exercisable. 12/60th of the shares subject to the option vest and become exercisable on October 31, 2019 and 1/60th of the shares subject to the option vest and become exercisable on each monthly anniversary thereafter, subject to the Reporting Person's continuous service through each vesting date. The option is immediately exercisable. 25% of the shares subject to the option vest and become exercisable on October 24, 2020 and 1/48th of the shares subject to the option vest and become exercisable on each monthly anniversary thereafter, subject to the Reporting Person's continuing service through each vesting date. /s/ Kendra Fox, as Attorney-in-Fact for Patrick John Finn 2026-02-17