X0609 4 2026-09-11 0001979414 NEONC TECHNOLOGIES HOLDINGS, INC. NTHI 0001998682 CHEN THOMAS C false 23975 SORRENTO PARK SUITE 205 CALABASAS CA 91302 true true true false CEO 0 Common Stock 2026-09-11 4 P false 5556 3.6 A 19261 I By IRA Common Stock 583531 D Common Stock 261242 I By HCWG LLC Common Stock 888148 I By NeuCen Biomedical Co. Ltd. Common Stock 2833961 I By TR Chen Third Family Limited Partnership. Common Stock 93253 I By Tien Duan Chen Trust Common Stock 948 I By Defined Benefit Plan Common Stock 2026-09-14 4 P false 5242 3.815 A 24503 I By IRA Includes shares of common stock held by certain members of Reporting Person's immediate family of which Reporting Person disclaims beneficial ownership except to the extent of his pecuniary interest, if any, therein. Such shares represent only Reporting Person's percentage interest in HCWG LLC. Shares held by NeuCen Biomedical Co. Ltd. ("NeuCen"). NeuCen is owned in part by Reporting Person's spouse. Reporting Person disclaims beneficial ownership of such shares except to the extent of his pecuniary interest, if any, therein. Shares held by T. R. Chen Third Family Limited Partnership, a NV limited partnership, of which Reporting Person and his spouse are the general partners with sole voting and dispositive power. Reporting Person disclaims beneficial ownership of such shares except to the extent of his pecuniary interest, if any, therein. Reporting Person disclaims beneficial ownership of such shares, except to the extent of his pecuniary interest, if any, therein. /S/ THOMAS C CHEN 2026-09-14