X0609 4/A 2026-04-10 2026-08-18 0001979414 NEONC TECHNOLOGIES HOLDINGS, INC. NTHI 0001998682 CHEN THOMAS C false 23975 SORRENTO PARK SUITE 205 CALABASAS CA 91302 true true true false Chief Scientific Officer 0 Common Stock 2026-04-10 4 P false 948 5.1677 A 948 I By IRA Common Stock 2026-04-24 4 P false 10000 4.80 A 10000 I By Defined Benefit Plan Common Stock 2026-08-14 4 P false 33787 3.8477 A 581059 D Common Stock 2026-08-17 4 P false 2472 4.0445 A 583531 D Common Stock 261242 I By HCWG LLC Common Stock 888148 I By NeuCen Biomedical Co. Ltd. Common Stock 2833961 I By TR Chen Third Family Limited Partnership Common Stock 93253 I By Tien Duan Chen Trust The aggregate number of shares of Issuer's common stock (the "Shares") purchased by the Reporting Person on the same day at different prices. Represents the weighted average purchase price. The Shares were purchased at prices ranging from $5.165 to $5.1722 per share, inclusive. Full information regarding the number of Shares sold at each price shall be provided to the Securities and Exchange Commission staff, Issuer or any security holder, upon request. Represents the weighted average purchase price. The Shares were purchased at prices ranging from $3.2299 to $4.0993 per share, inclusive. Full information regarding the number of Shares sold at each price shall be provided to the Securities and Exchange Commission staff, Issuer or any security holder, upon request. Includes shares of common stock held by certain members of Reporting Person's immediate family of which Reporting Person disclaims beneficial ownership except to the extent of his pecuniary interest, if any, therein. Represents the weighted average purchase price. The Shares were purchased at prices ranging from $4.04 to $4.1699 per share, inclusive. Full information regarding the number of Shares sold at each price shall be provided to the Securities and Exchange Commission staff, Issuer or any security holder, upon request. Such shares represent only Reporting Person's percentage interest in HCWG LLC. Shares held by NeuCen Biomedical Co. Ltd. ("NeuCen"). NeuCen is owned in part by Reporting Person's spouse. Reporting Person disclaims beneficial ownership of such shares except to the extent of his pecuniary interest, if any, therein. Shares held by T. R. Chen Third Family Limited Partnership, a NV limited partnership, of which Reporting Person and his spouse are the general partners with sole voting and dispositive power. Reporting Person disclaims beneficial ownership of such shares except to the extent of his pecuniary interest, if any, therein. Reporting Person disclaims beneficial ownership of such shares, except to the extent of his pecuniary interest, if any, therein. /S/ THOMAS C CHEN 2026-08-20