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<ownershipDocument>

    <schemaVersion>X0609</schemaVersion>

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    <periodOfReport>2026-07-16</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001510964</issuerCik>
        <issuerName>CV Sciences, Inc.</issuerName>
        <issuerTradingSymbol>CVSI</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001202557</rptOwnerCik>
            <rptOwnerName>CHEEVER CHARLIE E III</rptOwnerName>
        </reportingOwnerId>
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            <rptOwnerStreet1></rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity></rptOwnerCity>
            <rptOwnerState></rptOwnerState>
            <rptOwnerZipCode></rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
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            <isOfficer>0</isOfficer>
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            <isOther>0</isOther>
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    </reportingOwner>

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    <ownerSignature>
        <signatureName>Charles E. Cheever III</signatureName>
        <signatureDate>2026-09-09</signatureDate>
    </ownerSignature>
</ownershipDocument>
