X0609 4 2026-09-03 0001861123 Eikon Therapeutics, Inc. EIKN 0001796356 Column Group IV GP, LP false 1 LETTERMAN DR., BLDG D, SUITE DM-900 SAN FRANCISCO CA 94129 false false true false 0001796353 Column Group IV-A, LP false 1 LETTERMAN DR., BLDG D, SUITE DM-900 SAN FRANCISCO CA 94129 false false true false 0001796354 Column Group IV, LP false 1 LETTERMAN DR., BLDG D, SUITE DM-900 SAN FRANCISCO CA 94129 false false true false 0001931825 Column Group Opportunity III, LP false 1 LETTERMAN DR., BLDG D, SUITE DM-900 SAN FRANCISCO CA 94129 false false true false 0001932874 Column Group Opportunity III GP, LP false 1 LETTERMAN DR., BLDG D, SUITE DM-900 SAN FRANCISCO CA 94129 false false true false 0001932445 TCG Opportunity III GP, LLC false 1 LETTERMAN DR., BLDG D, SUITE DM-900 SAN FRANCISCO CA 94129 false false true false 0001614186 Kutzkey Tim false 1 LETTERMAN DR., BLDG D, SUITE DM-900 SAN FRANCISCO CA 94129 false false true false 0001606074 Svennilson Peter false 1 LETTERMAN DR., BLDG D, SUITE DM-900 SAN FRANCISCO CA 94129 false false true false false Common Stock 2026-09-03 4 P false 89200 11.5588 A 89200 I See footnote Common Stock 4312139 I By The Column Group IV, LP Common Stock 148840 I By The Column Group IV-A, LP Common Stock 1319164 I By The Column Group Opportunity III, LP The price reported in column 4 is a weighted average price. The securities were purchased in multiple transactions at prices ranging from $11.17 to $11.64. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of securities purchased at each separate price within the range set forth in this footnote. The securities are directly held by Peter Svennilson. The securities are directly held by The Column Group IV, LP ("TCG IV LP"). The Column Group IV GP, LP ("TCG IV GP LP") is the general partner of TCG IV LP and may be deemed to have voting and investment power with respect to securities directly held by TCG IV LP. Peter Svennilson and Tim Kutzkey are the managing partners of TCG IV GP LP and may each be deemed to share voting, investment and dispositive power with respect to securities directly held by TCG IV LP. Each of the Reporting Persons disclaims beneficial ownership of the securities noted herein, except to the extent of its or his pecuniary interest therein. The securities are directly held by The Column Group IV-A, LP ("TCG IV-A LP"). TCG IV GP LP is the general partner of the TCG IV-A LP and may be deemed to have voting and investment power with respect to securities directly held by the Reporting Person. Peter Svennilson and Tim Kutzkey are the managing partners of TCG IV GP LP and may each be deemed to share voting, investment and dispositive power with respect to securities directly held by TCG IV-A LP. Each of the Reporting Persons disclaims beneficial ownership of the securities noted herein, except to the extent of its or his pecuniary interest therein. The securities are directly held by The Column Group Opportunity III, LP ("TCG Opportunity III LP"). The Column Group Opportunity III GP, LP ("TCG Opportunity III GP LP") is the general partner of TCG Opportunity III LP. TCG Opportunity III GP, LLC is the general partner of TCG Opportunity III GP LP and the ultimate general partner of TCG Opportunity III LP. Each of TCG Opportunity III GP LP and TCG Opportunity III GP, LLC may be deemed to have voting, investment and dispositive power with respect to securities directly held by TCG Opportunity III LP. Peter Svennilson and Tim Kutzkey are the managing members of TCG Opportunity III GP, LLC and may each be deemed to share voting, investment and dispositive power with respect to securities directly held by TCG Opportunity III LP. Each of the Reporting Persons disclaims beneficial ownership of the securities noted herein, except to the extent of its or his pecuniary interest therein. /s/ The Column Group IV GP, LP, /s/ James Evangelista, Attorney-in-Fact 2026-09-08 /s/ The Column Group IV-A, LP. by The Column Group IV GP, LP, its general partner, /s/ James Evangelista, Attorney-in-Fact 2026-09-08 /s/ The Column Group IV, LP by The Column Group IV GP, LP, its general partner /s/ James Evangelista, Attorney-in-Fact 2026-09-08 /s/ The Column Group Opportunity III, LP, by The Column Group Opportunity GP, LP its general partner, by TCG Opportunity III GP, LLC, its general partner, /s/ James Evangelista, Attorney-in-Fact 2026-09-08 /s/ The Column Group Opportunity III GP, LP., by TCG Opportunity III GP, LLC, its general partner, /s/ James Evangelista, Attorney-in-Fact 2026-09-08 /s/ TCG Opportunity III GP, LLC, /s/ James Evangelista, Attorney-in-Fact 2026-09-08 /s/James Evangelista, as attorney-in-fact for Tim Kutzkey 2026-09-08 /s/James Evangelista, as attorney-in-fact for Peter Svennilson 2026-09-08