X0609 4 2026-08-25 0001661998 Q32 Bio Inc. QTTB 0001618273 Kalowski Lee false Q32 BIO INC. 830 WINTER STREET WALTHAM MA 02451 false true false false CFO and President false Common Stock 2026-08-25 4 S false 3972 16.56 D 138471 D Represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. These sales were automatic and not in the discretion of the Reporting Person. /s/ Eric Bell, Attorney-in-Fact 2026-08-27