X0609 4 2026-08-19 0001110803 ILLUMINA, INC. ILMN 0001307631 Meister Keith A. false C/O CORVEX MANAGEMENT LP 667 MADISON AVENUE NEW YORK NY 10065 true false false false false Common Stock 2026-08-19 4 S false 19884 202.37 D 2069541 I See Footnotes Common Stock 2026-08-19 4 S false 57544 203.16 D 2011997 I See Footnotes Common Stock 2026-08-19 4 S false 4759 204.16 D 2007238 I See Footnotes Common Stock 2026-08-19 4 S false 12813 205.00 D 1994425 I See Footnotes Common Stock 2026-08-20 4 S false 1132 207.65 D 1993293 I See Footnotes Common Stock 2026-08-20 4 S false 3563 208.55 D 1989730 I See Footnotes Common Stock 2026-08-20 4 S false 9078 209.68 D 1980652 I See Footnotes Common Stock 2026-08-20 4 S false 23638 210.66 D 1957014 I See Footnotes Common Stock 2026-08-20 4 S false 34009 211.9 D 1923005 I See Footnotes Common Stock 2026-08-20 4 S false 29805 212.83 D 1893200 I See Footnotes Common Stock 2026-08-20 4 S false 71939 213.36 D 1821261 I See Footnotes Common Stock 2026-08-20 4 S false 42218 214.57 D 1779043 I See Footnotes Common Stock 2026-08-20 4 S false 18405 215.62 D 1760638 I See Footnotes Common Stock 2026-08-20 4 S false 15263 216.88 D 1745375 I See Footnotes Common Stock 2026-08-20 4 S false 21147 217.72 D 1724228 I See Footnotes Common Stock 2026-08-20 4 S false 5693 218.46 D 1718535 I See Footnotes Common Stock 2026-08-20 4 S false 9348 219.82 D 1709187 I See Footnotes Common Stock 2026-08-21 4 S false 4528 210.45 D 1704659 I See Footnotes Common Stock 2026-08-21 4 S false 7151 211.54 D 1697508 I See Footnotes Common Stock 2026-08-21 4 S false 13050 212.65 D 1684458 I See Footnotes Common Stock 2026-08-21 4 S false 6821 213.81 D 1677637 I See Footnotes Common Stock 2026-08-21 4 S false 13668 214.64 D 1663969 I See Footnotes Common Stock 2026-08-21 4 S false 9365 215.61 D 1654604 I See Footnotes Common Stock 2026-08-21 4 S false 12602 216.44 D 1642002 I See Footnotes Common Stock 2026-08-21 4 S false 8187 217.84 D 1633815 I See Footnotes Common Stock 2026-08-21 4 S false 86825 218.60 D 1546990 I See Footnotes Common Stock 2026-08-21 4 S false 133256 219.47 D 1413734 I See Footnotes Common Stock 2026-08-21 4 S false 3883 220.13 D 1409851 I See Footnotes Common Stock 6780 D These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister. For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $201.59 to $202.58. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (3)-(30) to this Form 4. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $202.59 to $203.58. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $203.65 to $204.61. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $204.72 to $205.11. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $207.01 to $207.91. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $208.02 to $209.01. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $209.11 to $210.10. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $210.11 to $211.09. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $211.14 to $212.13. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $212.14 to $213.12. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $213.14 to $214.13. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $214.14 to $215.11. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $215.14 to $216.13. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $216.14 to $217.13. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $217.14 to $218.13. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $218.14 to $219.13. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $219.15 to $220.00. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $210.01 to $210.99. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $211.06 to $212.04. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $212.06 to $213.05. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $213.07 to $214.06. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $214.07 to $215.06. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $215.07 to $216.06. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $216.07 to $217.06. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $217.07 to $218.05. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $218.07 to $219.06. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $219.07 to $220.06. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $220.07 to $220.43. /s/ Keith Meister 2026-08-21