X0609 4 2026-08-14 0001880438 AN2 Therapeutics, Inc. ANTX 0001331852 Zakrzewski Joseph S false C/O AN2 THERAPEUTICS, INC. 1300 EL CAMINO REAL, SUITE 100 MENLO PARK CA 94025 true false false false false Common Stock 2026-08-14 4 G false 405880 0 D 0 I See footnote Common Stock 145538 D Reflects a gift of shares to the children of the Reporting Person. The shares are held by Nancy Zakrzewski TTEE Z3 Trust U/A DTD 11/25/14 ("Z3 Trust"). The Reporting Person disavows beneficial ownership of the shares held by Z3 Trust. /s/ Lucy Day, Attorney-in-Fact for Joseph S. Zakrzewski 2026-08-14