X0609 4 2026-06-09 0001785279 Metagenomi Therapeutics, Inc. MGX 0001492749 Reid Laurence false C/O METAGENOMI THERAPEUTICS, INC. 5959 HORTON STREET, 7TH FLOOR EMERYVILLE CA 94608 true false false false false Stock Option (Right to Buy) 1.23 2026-06-09 4 A false 17400 0 A 2036-06-08 Common Stock 17400 17400 D The shares subject to this option shall vest and become exercisable upon the earlier of (i) the one-year anniversary of the Grant Date or (ii) the date of the Company's 2027 annual meeting of stockholders, subject to the Reporting Person's continued service with the Issuer on such vesting date. /s/ Matthew L. Wein, attorney-in-fact 2026-06-11