X0508 4 2026-02-26 0001719714 Mereo BioPharma Group plc MREO 0001863107 Bender Jeremy C/O MEREO BIOPHARMA GROUP PLC 4TH FLOOR, ONE CAVENDISH PLACE LONDON X0 W1G 0QF UNITED KINGDOM true false false false false Share Options (Right to buy) 0.39 2026-02-26 4 A false 66000 0 A 2036-02-26 American Depositary Shares 66000 66000 D Deferred Restricted Stock Units 2026-02-26 4 A false 117533 A American Depository Shares 117533 117533 D Vests in substantially equal monthly installments over a one year period from the February 26, 2026 grant date. Each American Depositary Share ("ADS") represents five ordinary shares, nominal value GBP 0.003 per ordinary share, of the Issuer. Deferred restricted stock units ("DRSU") are granted to non-executive directors who elected to receive DRSUs in the form of ADSs in lieu of annual cash compensation. DRSUs vest in substantially equal monthly installments over the plan year following the grant date. Payment of DRSUs in ADSs will generally be made 180 days following separation of service. /s/ Christine Fox, by power of attorney 2026-02-27