X0508 4 2026-02-24 0001745999 Beam Therapeutics Inc. BEAM 0001786322 Ciaramella Giuseppe C/O BEAM THERAPEUTICS INC., 238 MAIN STREET CAMBRIDGE MA 02142 false true false false President true Common Stock 2026-02-24 4 M false 35000 17 A 225216 D Common Stock 2026-02-24 4 S false 35000 32.0012 D 190216 D Stock Option (Right to Buy) 17 2026-02-24 4 M false 35000 0 D 2030-02-05 Common Stock 35000 397313 D The shares of Common Stock were sold pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 30, 2025. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions ranging from $32.00 to $32.04, inclusive. The Reporting Person undertakes to provide to Beam Therapeutics Inc. ("BEAM"), any security holder of BEAM or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range. The option vests as to 25% on the first anniversary of the of the vesting commencement date, February 5, 2020, and at a rate of 2.78% each month thereafter until the option is fully vested. By: /s/ Christine Bellon, Attorney-in-fact 2026-02-26