X0508 4 2026-02-05 false 0001631574 Wave Life Sciences Ltd. WVE 0001657675 Vargeese Chandra C/O WAVE LIFE SCIENCES LTD., 733 CONCORD AVE. CAMBRIDGE MA 02138 false true false false See Remarks false Ordinary Shares 2026-02-05 4 A false 45625 0.00 A 411474 D Ordinary Shares 2026-02-09 4 S false 3228 13.45 D 408246 D Share Option (right to buy) 12.75 2026-02-05 4 A false 273750 0.00 A 2036-02-05 Ordinary Shares 273750 273750 D Consists of restricted share units (RSUs). The RSUs vest in four equal annual installments of 25% on February 8, 2027 through February 8, 2030. Includes 3,162 ordinary shares acquired on July 15, 2025, and January 14, 2026, under the issuer's 2019 Employee Share Purchase Plan. On February 9, 2026, the reporting person sold 3,228 ordinary shares solely to cover taxes associated with the vesting of restricted share units ("RSUs") on February 8, 2026. These sales were made pursuant to a provision in the reporting person's RSU agreement that requires automatic sales of shares to cover tax withholding obligations. The option vests as to 25% of the shares on February 8, 2027, and vests as to an additional 6.25% of the shares quarterly thereafter until February 8, 2030. Chief Technology Officer, Head of Platform Discovery Sciences /s/ Chandra Vargeese 2026-02-11