X0508 4 2026-02-02 0001680581 Fulcrum Therapeutics, Inc. FULC 0001916566 Tourangeau Greg C/O FULCRUM THERAPEUTICS, INC. 26 LANDSDOWNE STREET CAMBRIDGE MA 02139 false true false false Principal Accounting Officer false Stock Option (right to buy) 10.72 2026-02-02 4 A false 57000 0.00 A 2036-02-01 Common Stock 57000 57000 D This option was granted on February 2, 2026 and is scheduled to vest in equal quarterly installments over four years beginning on the vesting commencement date of January 1, 2026, subject to the reporting person's continued service on each such vesting date. /s/ Gregory Tourangeau 2026-02-04