X0508 4 2025-12-11 0001585608 Jaguar Health, Inc. JAGX 0001008377 CONTE LISA A C/O JAGUAR HEALTH, INC. 200 PINE ST., STE 400 SAN FRANCISCO CA 94104 true true false false See Remarks false Common Stock 2025-12-11 4 A false 28592 0 A 29258 D Stock Option (right to buy) 1.44 2025-12-11 4 A false 28592 0 A 2035-12-11 Common Stock 28592 28592 D Granted pursuant to the issuer's 2014 Stock Incentive Plan. The restricted stock unit and option grants were approved by the issuer's board of directors on December 11, 2025. Each restricted stock unit represents a contingent right to receive one share of the issuer's voting common stock. The restricted stock units vest on December 11, 2026. Vested shares will be delivered to the reporting person on the vesting date provided in the grant notice. The options will vest ratably on a monthly basis over 12 months from the grant date, so long as the executive remains employed by the issuer. Chief Exec. Officer & President /s/ Lisa A. Conte 2026-01-21