X0508 4 2026-01-09 0001339970 aTYR PHARMA INC ATYR 0001305178 Broadfoot Jill Marie 10240 SORRENTO VALLEY ROAD SUITE 300 SAN DIEGO CA 92121 false true false false Chief Financial Officer false Common Stock 35104 D Employee Stock Option (right to buy) 0.7127 2026-01-09 4 A false 412500 0 A 2036-01-09 Common Stock 412500 412500 D Includes 841 shares acquired on May 15, 2025 and 2,500 shares acquired on November 14, 2025 under the Company's 2015 Employee Purchase Plan. The shares subject to this option shall vest and become exercisable in 36 equal monthly installments beginning February 9, 2026, such that this option will be fully exercisable on January 9, 2029. This option is subject to accelerated vesting upon termination without cause upon change of control of the issuer. /s/ Nancy E. Denyes, attorney-in-fact 2026-01-09