X0508 4 2025-12-15 false 0001572616 FRACTYL HEALTH, INC. GUTS 0001667672 Rajagopalan Harith 3 VAN DE GRAAFF DRIVE SUITE 200 BURLINGTON MA 01803 true true false false Chief Executive Officer false Stock Option (right to buy) 2.24 2025-12-15 4 A false 2486302 0 A 2035-12-14 Common Stock 2486302 2486302 D The stock option vests and becomes exercisable in equal installments on each of the first three anniversaries of the grant date, subject to the Reporting Persons's continuing in employment through each such vesting date. /s/ Harith Rajagopalan 2025-12-17