X0508 4 2025-09-05 0001785279 Metagenomi, Inc. MGX 0001995657 Wapnick Pamela C/O METAGENOMI, INC. 5959 HORTON STREET, 7TH FLOOR EMERYVILLE CA 94608 false true false false Chief Financial Officer false Common Stock 2025-09-05 4 S false 1576 1.81 D 70532 D Common Stock 2025-12-01 4 A false 120000 1.60 A 190532 D These shares of common stock were automatically sold for the purpose of satisfying the Reporting Person's tax withholding obligations upon the vesting of certain restricted stock units ("RSUs") granted to the Reporting Person on April 1, 2024, and does not represent a volitional trade by the Reporting Person. These shares represent RSUs. 50% of the RSUs shall vest on December 5, 2026, with the remainder vesting on December 5, 2027, subject to the Reporting Person's continued service with the Issuer on each such vesting date. /s/ Matthew L. Wein, attorney-in-fact 2025-12-01