X0609 4 2026-05-29 0 0002019410 Caris Life Sciences, Inc. CAI 0001180770 POSTE GEORGE false C/O CARIS LIFE SCIENCES, INC. 750 W. JOHN CARPENTER FREEWAY, SUITE 800 IRVING TX 75039 1 0 0 0 0 Common Stock 2026-05-29 4 A 0 1600 15.62 A 17729 D Common Stock 511702 I By Family Trust Shares issued in lieu of cash compensation for 2026 board retainer fees. Number of shares determined by dividing the cash retainer earned by the ten trading day average of the daily volume weighted average price per share through and including May 29, 2026. Amount reflects the previous transfer by the Reporting Person of 204,108 shares of Common Stock from direct ownership to a family trust. Following the transfer, these shares are held indirectly by the Reporting Person through the family trust and are reflected in the indirect ownership line. The transfer did not change the Reporting Person's aggregate beneficial ownership of these securities. /s/ J. Russel Denton, Attorney-in-Fact 2026-06-02