X0508 4 2026-02-20 0 0002022416 Silexion Therapeutics Corp SLXN 0001727789 Shirvan Mitchell C/O SILEXION THERAPEUTICS CORP 12 ABBA HILLEL ROAD RAMAT GAN L3 5250606 ISRAEL 0 1 0 0 CSO and CDO 0 Ordinary Shares 2026-02-20 4 A 0 49726 0 A 50707 D Stock Option (right to buy Ordinary Shares) 907.71 2024-08-15 2032-06-07 Ordinary Shares 478 478 D The number of ordinary shares, par value $0.0135 per share ("ordinary shares"), reported in this Form 4 reflect adjustments relative to the Form 3 filed by the Reporting Person due to the 1-for 9 and 1-for-15 reverse share splits effected by the Issuer on November 29, 2024 and July 29, 2025, respectively. The transaction reported in this row consists of the grant to the Reporting Person by the Issuer of fully vested restricted share units (RSUs), which were immediately settled for underlying ordinary shares, in respect of the Reporting Person's services as an officer of the Issuer. The grant was approved by the Issuer's board of directors. There were no transactions effected in respect of the securities reported in this row, and the holdings in this row are being included for informational purposes only. The number of options to purchase ordinary shares, underlying ordinary shares, and the exercise price of those options reported in this row have been adjusted to reflect a 1-for-9 reverse share split effected by the Issuer on November 29, 2024 and a 1-for-15 reverse share split effected by the Issuer on July 29, 2025. /s/ Mirit Horenshtein Hadar, Attorney-in-fact 2026-02-23