X0508 4 2026-01-16 0001133416 GALECTIN THERAPEUTICS INC GALT 0001694903 Uihlein Richard E 4960 PEACHTREE INDUSTRIAL BLVD SUITE 240 NORCROSS GA 30071 true false true false false Common Stock 2026-01-16 4 A false 13158 3.04 A 10332676 D Common Stock 27710 I By Ed Uihlein Family Foundation Stock option (right to buy) 3.04 2026-01-16 4 A false 60000 0 A 2036-01-16 Common Stock 60000 60000 D The stock options were issued pursuant to the Galectin Therapeutics, Inc. 2019 Omnibus Equity Incentive Plan. The options vest 100% on December 31, 2026. These restricted shares were issued pursuant to the Galectin Therapeutics Inc. 2019 Omnibus Equity Incentive Plan in lieu of a cash retainer and meeting fees of $40,000 for 2026. Restrictions on the shares lapse at a rate of 25% at the end of each calendar quarter in 2026. The reporting person is president and director of Ed Uihlein Family Foundation, a not-for-profit corporation. The reporting person has no pecuniary interest in the shares, however, he shares voting and dispositive power over the shares and, therefore, remains the beneficial owner of the shares solely for the purposes of Section 13(d) of the Securities Exchange Act of 1934. Jack W. Callicutt, by power of attorney 2026-01-21