X0508 4 2025-11-17 0001133416 GALECTIN THERAPEUTICS INC GALT 0001725595 LEWIS JOEL C/O GALECTIN THERAPEUTICS INC. 4960 PEACHTREE INDUSTRIAL BLVD., STE 240 NORCROSS GA 30071 true true false false President and CEO true Common Stock 2025-11-17 4 M false 15680 2.39 A 848272 D Common Stock 2025-11-17 4 S false 15680 6.0359 D 832592 D Common Stock 2025-11-18 4 M false 6783 2.39 A 839375 D Common Stock 2025-11-18 4 S false 6783 6.1511 D 832592 D Common Stock 2000 I as USTA custodian for a minor child Stock option (right to buy) 2.39 2025-11-17 4 M false 15680 0 D 2018-12-14 2027-12-14 Common Stock 15680 6783 D Stock option (right to buy) 2.39 2025-11-18 4 M false 6783 0 D 2018-12-14 2027-12-14 Common Stock 6783 0 D The reported transaction was made pursuant to a Rule 10b5-1 plan adopted by the reporting person on April 17, 2025, as disclosed in the Issuer?s Quarterly Report on Form 10-Q, filed with the SEC on August 14, 2025. The options vested 100% on December 14, 2018. These shares are held of record by the Reporting Person as custodian for a minor child under the Uniform Transfer to Minors Act. The Reporting Person disclaims beneficial ownership of these securities, and the filing of this report is not an admission that the Reporting Person is the beneficial owner of these securities for purpose of Section 16 or for any other purpose. The shares were sold in multiple transactions at prices ranging from $6.00 to $6.10. This amount represents the weighted average sale price of such transactions. The reporting person undertakes to provide full information regarding the number of shares sold at each separate price upon request by the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer. The shares were sold in multiple transactions at prices ranging from $6.00 to $6.32. This amount represents the weighted average sale price of such transactions. The reporting person undertakes to provide full information regarding the number of shares sold at each separate price upon request by the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer. Jack W. Callicutt, by power of attorney 2025-11-19