X0508 4 2025-11-05 0001133416 GALECTIN THERAPEUTICS INC GALT 0001725595 LEWIS JOEL C/O GALECTIN THERAPEUTICS INC. 4960 PEACHTREE INDUSTRIAL BLVD., STE 240 NORCROSS GA 30071 true true false false President and CEO true Common Stock 2025-11-05 4 M false 200 2.39 A 832792 D Common Stock 2025-11-05 4 S false 200 6.00 D 832592 D Common Stock 2000 I as USTA custodian for a minor child Stock option (right to buy) 2.39 2025-11-05 4 M false 200 0 D 2018-12-14 2027-12-14 Common Stock 200 24230 D The reported transaction was made pursuant to a Rule 10b5-1 plan adopted by the reporting person on April 17, 2025, as disclosed in the Issuer?s Quarterly Report on Form 10-Q, filed with the SEC on August 14, 2025. The options vested 100% on December 14, 2018. These shares are held of record by the Reporting Person as custodian for a minor child under the Uniform Transfer to Minors Act. The Reporting Person disclaims beneficial ownership of these securities, and the filing of this report is not an admission that the Reporting Person is the beneficial owner of these securities for purpose of Section 16 or for any other purpose. Jack W. Callicutt, by power of attorney 2025-11-07