X0609 4 2026-06-30 0 0001682639 HYPERION DEFI, INC. HYPD 0001575385 Strahlman Ellen R false C/O HYPERION DEFI, INC. 3090 NOWITZKI WAY, SUITE 300 DALLAS TX 75219 1 0 0 0 0 Common Stock, par value $.0001 2026-06-30 4 A 0 58917 0 A 150078 D Represents restricted stock units that fully vest on the earlier of June 30, 2027 and the date of the Issuer's 2027 annual meeting of stockholders; provided, however, that such awards shall vest immediately in full (a) upon the date on which a Corporate Transaction (as defined in the Issuer's Amended and Restated 2018 Omnibus Stock Incentive Plan) has occurred, or (b) the date on which the Reporting Person's service on the Issuer's Board of Directors (the "Board") concludes for any reason other than a self-initiated decision by such Reporting Person to step down from the Board. /s/ Ellen Strahlman 2026-07-01