X0508 4 2026-02-24 0 0001640266 Voyager Therapeutics, Inc. VYGR 0001842523 Jorgensen Nathan D. C/O VOYAGER THERAPEUTICS, INC. 75 HAYDEN AVENUE LEXINGTON MA 02421 0 1 0 0 Chief Financial Officer 1 Common Stock 2026-02-24 4 S 0 4668 3.77 D 151416 D Represents shares of common stock of Voyager Therapeutics, Inc. (the "Corporation") sold, pursuant to a durable automatic sale instruction adopted by the reporting person on May 9, 2025, effecting the sell-to-cover election of the reporting person to satisfy tax withholding obligations, in connection with the vesting of restricted stock units on February 21, 2026. The sales do not represent a discretionary trade by the reporting person. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $3.61 to $3.86, inclusive. The reporting person undertakes to provide to the Corporation, any security holder of the Corporation, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (2) to this Form 4. Exhibit 24.1: Limited Power of Attorney /s/ Gregory Shiferman, as Attorney-in-Fact for Nathan D. Jorgensen 2026-02-26