X0508 4 2026-01-09 0 0001609550 Inspire Medical Systems, Inc. INSP 0001932219 Rondoni John C/O INSPIRE MEDICAL SYSTEMS, INC. 5500 WAYZATA BLVD., SUITE 1600 GOLDEN VALLEY MN 55416 0 1 0 0 See Remarks 1 Common Stock 2026-01-09 4 S 0 109 100.00 D 13797 D Includes 140 shares acquired under the Issuer's 2018 Employee Stock Purchase Plan since the Reporting Person's Form 4 dated May 21, 2025. Title: Chief Product and Innovation Officer. All sale transactions reported herein were made pursuant to a Rule 10b5-1 trading plan dated May 28, 2025. /s/ Bryan Phillips, Attorney-in-Fact for John Rondoni 2026-01-12