X0508 4 2026-01-02 0 0001377121 Protagonist Therapeutics, Inc PTGX 0001475714 Williams Lewis T C/O PROTAGONIST THERAPEUTICS, INC. 7707 GATEWAY BLVD., SUITE 140 NEWARK CA 94560-1160 1 0 0 0 0 Common Stock 2026-01-02 4 A 0 2695 0 A 7825 D Stock Option (right to buy) 87.18 2026-01-02 4 A 0 3762 0 A 2036-01-02 Common Stock 3762 3762 D Represents grant of restricted stock units payable solely in common stock that will vest in full on January 15, 2027, subject to the Reporting Person's continued service to the Issuer through the vesting date. The stock option vests in 12 equal monthly installments following January 2, 2026, subject to the Reporting Person's continued service to the Issuer through each applicable vesting date. /s/ Matthew Gosling, Attorney-in-Fact for Lewis T. "Rusty" Williams 2026-01-06